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首頁 > 師資隊伍 > 教師 > 水環境保護教研所 > 正文

水環境保護教研所

周小紅

郵箱:xhzhou@mail.tsinghua.edu.cn

電話:13810593267

地點:bevictor伟德官网中意清華環境節能樓426房間

教育背景

1998.09-2002.07 同濟大學 環境工程 學士

2002.09-2007.07 bevictor伟德官网 環境工程 博士


工作履曆

2009.07-至今          bevictor伟德官网 bevictor伟德官网 講師、副教授、長聘副教授

2014.02-2014.11      英國南安普頓大學光電中心 訪問學者

2008.09-2009.03    加拿大阿爾伯塔大學 訪問學者

2007.07-2009.06    bevictor伟德官网 博士後


學術兼職

2021.07-至今 Frontier系列新刊Frontiers in Analytical Science 副主編

2021.06-至今 SCI源刊Frontiers in Bioscience-Landmark 編委/特刊客座編輯

2020.04-至今 SCI源刊Biosensors  編委/特刊客座編輯

2018.02-至今 EI源刊Micro and Nanosystems 編委

2015.03-至今 SCI源刊Scientific Reports 編委

2017 智利自然科學基金委FONDECYT 國際評委

2017 美國Kentucky Science and Engineering Foundation 國際評委

2017.07-至今 生物傳感、生物芯片和納米生物技術專業委員會 委員

2016.01-至今 中國儀器儀表學會分析儀器分會在線儀器專委會 委員

2011.01-至今 IEEE、美國ACS、國際水協會IWA 會員



研究領域

環境監測、環境污染物生物化學分析技術、生物傳感器及納米生物傳感器


研究概況

  1. 國家自然科學基金重大項目,環境介質中的病毒識别與傳播規律,2021/01-2025/12,在研,參加

  2. bevictor伟德官网春風基金抗疫專項,CRISPR/Cas13a結合核酸自驅動放大的病毒現場檢測試紙條及其定量檢測裝置,2020/09-2022/09,在研,主持

  3. 中國工程院應急科技攻關項目,城市水系統關鍵節點新型冠狀病毒存在風險識别,2020/02-2021/02,結題,參加

  4. 國家自然科學基金面上基金項目,分子對接輔助優化水中環境雌激素拟/抗活性同步檢測的生物傳感分析技術,2020/01-2023/12,在研,主持

  5. 國家重點研發計劃,村鎮社區環境監測及修複關鍵技術研發,2019/11-2022/12,在研,參加

  6. 國家重點研發計劃,場地地下水污染快速識别與風險監測管控技術,2020/01-2022/12,在研,參加

  7. EPSC自由申請課題,微囊藻毒素廣譜性抗體篩選及其倏逝波免疫傳感分析應用,2019/08-2021/08,結題,主持

  8. 北京市自然科學基金-海澱原始創新聯合基金重點項目,水中抗生素快速定量檢測的倏逝波生物傳感分析技術,2019/01-2021/12,結題,主持

  9. bevictor伟德官网-劍橋大學聯合科研基金,功能化二維材料表面等離子體共振增強機制及其用于環境雌激素傳感分析研究,2019/01-2021/07,結題,主持

  10. 北京市自然科學基金面上項目,基于受體的再生水中雌激素效應檢測倏逝波熒光傳感技術,2018/01-2019/12,結題,主持

  11. EPSC聯合基金,核受體介導的環境内分泌幹擾物效應檢測生物傳感器技術,2017/05-2019/04,結題,聯合主持

  12. 國家自然科學基金中英合作交流項目,用于環境生物檢測的多通道集成光波導芯片,2017/04-2019/03,結題,主持

  13. 國家自然科學基金面上基金項目,基于工程化适配體的水中抗生素快速定量倏逝波傳感檢測技術,2017/01-2020/12,結題,主持

  14. 國家科技部重大儀器開發專項,多指标平面波導生物芯片的開發,2012/09-2017/09,結題,參與

  15. 國家科技部863計劃,水質安全生物預警監測技術與系統,2014/01-2017/12,結題,參加

  16. 北京市自然科學基金項目,基于微電極測試的污水深度處理反硝化生物濾池脫氮模型,2013/01-2015/12,結題,主持

  17. bevictor伟德官网國際科技合作項目,基于功能核酸的重金屬檢測技術研究,2013/01-2014/12,結題,主持

  18. 國家自然科學基金青年基金,人工金屬氧化物納米顆粒在污水生物處理系統中的歸趨及對微生物聚集體活性的影響,2012/01-2014/12,結題,負責人


獎勵與榮譽

2021年 總微囊藻毒素在線分析儀,中國發明協會發明創業獎創新獎二等獎/第48屆日内瓦國際發明展會金獎,排名第一

2020年 中國産學研合作創新獎、中國儀器儀表學會朱良漪分析儀器青年創新獎、國家生态環境保護專業技術青年拔尖人才

2015年 bevictor伟德官网學生工作先進個人

2014年 微量有毒污染物快速高靈敏檢測的生物傳感技術及儀器,教育部技術發明獎一等獎,排名第六

2014年 入選“bevictor伟德官网桑坦德銀行資助項目”

2014年《污水處理在線監測儀器原理與應用(第二版)》獲得“2014年中國石油和化學工業優秀出版物獎·圖書獎”二等獎(排名第二)

2011年 教育部“長江學者和創新團隊發展計劃”創新團隊,成員


學術成果

以第一/通訊作者在Nature Communications、Light: Science & Applications、B&B、EST等發表SCI論文60餘篇,論文H-index為26;以第一發明人授權國家發明專利9項,實現轉化與應用3項。

近5年發表的同行評議論文(#共同一作;*通訊):


  1. H.H. Zhu, J. Zou, H. Zhang, Y.Z. Shi, S.B. Luo, N. Wang, H. Cai, L.X. Wan, B. Wang, X.D. Jiang*, J. Thompson, X.S. Luo, X.H. Zhou*, L.M. Xiao*, W. Huang, L Patrick, M. Gu*, L.C. Kwek*, and A. Q. Liu*. Space-efficient optical computing and an integrated chip of diffractive neural network. Nature Communications, 2022, 13, 1044.

  2. Qian Zhu, Xiaohong Zhou*. A colorimetric sandwich-type bioassay for SARS-CoV-2 using a hACE2-based affinity peptide pair. Journal of Hazardous Materials, 2022, 425, 127923.

  3. Jinchuan Liu, Yunpeng Xing, Boyuan Xue, Xiaohong Zhou*. Nanozyme enhanced paper-based biochip with a smartphone readout system for rapid detection of cyanotoxins in water. Biosensors and Bioelectronics, 2022, 205, 114099.

  4. Lanhua Liu#, Xuejun Zhang#, Qian Zhu#, Kaiwei Li, Yun Lu, Xiaohong Zhou*, Tuan Guo*. Ultrasensitive detection of endocrine disruptors via superfine plasmonic spectral combs. Light: Science and Applications, 2021, 10, 181.

  5. Qian Zhu, Lanhua Liu, Ruoyu Wang, Xiaohong Zhou*. A split aptamer (SPA)-based sandwich-type biosensor for facile and rapid detection of streptomycin. Journal of Hazardous Materials, 2021, 403, 123941.

  6. Yihan Yang, Jinchuan Liu, Xiaohong Zhou*. A CRISPR-based and post-amplification coupled SARS-CoV-2 detection with a portable evanescent wave biosensor. Biosensors and Bioelectronics, 2021, 190, 113418.

  7. Jinchuan Liu, Yihan Yang, Qian Zhu, Zhanhui Wang, Guanjiu Hu, Hanchang Shi, Xiaohong Zhou*. ELISA-Based Method for Variant-Independent Detection of Total Microcystins and Nodularins via a Multi-immunogen Approach. Environmental Science & Technology, 2021, 55, 19, 12984-12993.

  8. Jinchuan Liu, Yunpeng Xing, Xiaohong Zhou*, George Y. Chen*, Hanchang Shi. Light-sheet skew rays enhanced U-shaped fiber-optic fluorescent immunosensor for microcystin-LR. Biosensors and Bioelectronics, 2021, 176, 112902.

  9. Yangyang Chen#, Qian Zhu#, Xiaohong Zhou*, Ruoyu Wang, Zhenchuan Yang. Reusable, facile, and rapid aptasensor capable of online determination of trace mercury. Environmental International, 2021, 146, 106181.

  10. Jinbiao Ma, Manman Du, Can Wang*, Xinwu Xie*, Hao Wang, Tie Li*, Shixing Chen, Lixia Zhang, Shun Mao, Xiaohong Zhou*, Min Wu. Rapid and sensitive detection of Mycobacterium tuberculosis by an enhanced nanobiosensor. ACS Sensors, 2021, 6(9), 3367-3376.

  11. Xiaohong Zhou*, Abdul Ghaffar Memon, Weiming Sun, Fang Fang, Jinsong Guo*. Fluorescent probe for Ag+ detection using SYBR GREEN I and C-C mismatch. Biosensors, 2021, 11, 6.

  12. Weiming Sun, Lanhua Liu, Abdul Ghaffar Memon, Xiaohong Zhou*, Hongwei Zhao*. Waveguide-based fluorescent immunosensor for the simultaneous detection of carbofuran and 3-hydroxy-carbofuran. Biosensors, 2020, 10, 191. Selected as Title Story.

  13. Xiaohong Zhou*, Qian Zhu, Yihan Yang. Aptamer-integrated nucleic acid circuits for biosensing: Classification, challenges and perspectives. Biosensors and Bioelectronics, 2020, 165, 112422.

  14. Xuewen Yi, Zhanqi Gao, Lanhua Liu, Qian Zhu, Guanjiu Hu*, Xiaohong Zhou*. Acute toxicity assessment of drinking water source with luminescent bacteria: Impact of environmental conditions and a case study in Luoma Lake, East China. Frontier Environmental Science and Engineering, 2020, 14(6), 109.

  15. Yunpeng Xing, Qian Zhu, Xiaohong Zhou*, Peishi Qi. A dual-functional smartphone-based sensor for colorimetric and chemiluminescent detection: A case study for fluoride concentration mapping. Sensors and Actuators B: Chemical, 2020, 319, 128254.

  16. Yunpeng Xing, Qian Zhu, Xiaohong Zhou*, Peishi Qi*. A gold nanoparticle-based colorimetric mercury(II) biosensor using a DNA probe with phosphorothioate RNA modification and exonuclease III-assisted signal amplification. Microchimica Acta, 2020, 187, 214.

  17. Abdul Ghaffar Memon, Yunpeng Xing, Xiaohong Zhou*, Ruoyu Wang, Lanhua Liu, Siyu Zeng*, Miao He*, Mei Ma. Ultrasensitive colorimetric aptasensor for Hg2+ detection using Exo-III assisted target recycling amplification and unmodified AuNPs as indicators. Journal of Hazardous Materials, 2020, 384, 120948.

  18. Ruoyu Wang#, Qiansen Zhang#, Yi Zhang, Hanchang Shi, Kim Truc Nguyen, Xiaohong Zhou*. Unconventional split aptamers cleaved at functionally essential sites preserve biorecognition capability. Analytical Chemistry, 2019, 91, 15811-15817. Selected as Supplementary Cover Article.

  19. Kaidong Xia, Zhihong Li, Xiaohong Zhou*. Ultrasensitive detection of a variety of analytical targets based on a functionalized low-resistance AuNPs/beta-Ni(OH)2 nanosheets/Ni foam sensing platform. Advanced Functional Materials, 2019, 29, 1904922.

  20. Ruoyu Wang, Xiyu Zhu, Yunpeng Xing, Abdul Ghaffar Memon, Hanchang Shi, Xiaohong Zhou*. Multitag-regulated cascade reaction: A generalizable ultrasensitive microRNA biosensing approach for cancer prognosis. ACS Applied Materials & Interface, 2019, 11, 36444-36448.

  21. Yangyang Chen, Jinchuan Liu, James S. Wilkinson*, Xiaohong Zhou*. Optical biosensors based on refractometric sensing schemes: A review. Biosensors and Bioelectronics, 2019, 144, 111693.

  22. Ruoyu Wang, Xueqi Wu, Xiyu Zhu, Hanchang Shi, Xiaohong Zhou*. A photoregulated split aptaswitch for small molecules with improved sensitivity. Chemical Communications, 2019, 55, 9555-9558.

  23. Lanhua Liu, Xiaohong Zhou*, Yun Lu, Hanchang Shi, Mei Ma, Tong Yu. Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water samples. Environment International, 2019, 132, 105091.

  24. Qian Zhu, Lanhua Liu, Xiaohong Zhou*, Mei Ma. In silico study of molecular mechanisms of action: Estrogenic disruptors among phthalate esters. Environmental Pollution, 2019, 255, 113293.

  25. Xiyu Zhu, Ruoyu Wang, Kaidong Xia, Xiaohong Zhou*, Hanchang Shi. Nucleic acid functionalized fiber optic probes for sensing in evanescent wave: optimization and application. RSC Advances, 2019, 9, 2316-2324.

  26. Abdul Ghaffar Memon, Xiaohong Zhou*, Yunpeng Xing, Ruoyu Wang, Lanhua Liu, Mohsin Khan, Miao He*. Label-free colorimetric nanosensor with improved sensitivity for Pb2+ in water by using a truncated 8-17 DNAzyme. Frontiers of Environmental Science & Engineering, 2019, 13, 12.

  27. Lanhua Liu#, Didi Shan#, Xiaohong Zhou, Hanchang Shi, Baodong Song, Floris Falke, Arne Leinse, R.G. Heideman. TriplexTM waveguide-based fluorescence biosensor for multichannel environmental contaminants detection. Biosensors and Bioelectronics, 2018, 106, 117-121.

  28. Jinchuan Liu, Xiaohong Zhou*, Hanchang Shi. An optical biosensor-based quantification of microcystin synthetase A gene: Early warning of toxic cyanobacterial blooming. Analytical Chemistry, 2018, 90, 2362-2368.

  29. Lanhua Liu, Xiaohong Zhou*, Ruiman Ma, Miao He, Hanchang Shi, Qian Yi. High-throughput biomolecular interaction analysis probing by an array fluorescent biosensor platform, Sensors and Actuators B: Chemical, 2018, 259,888-893.

  30. Qian Zhu, Lanhua Liu, Yunpeng Xing, Xiaohong Zhou*. Duplex functional G-quadruplex/NMM fluorescent probe for label-free detection of lead(II) and mercury(II) ions, Journal of Hazardous Materials, 2018, 355, 50-55.

  31. Ruoyu Wang, Xiaohong Zhou*, Bo Liedberg, Xiyu Zhu, Abdul Ghaffar Memon, Hanchang Shi. Screening criteria for qualified antibiotic targets in unmodified gold nanoparticles-based aptasensing. ACS Applied Materials & Interfaces, 2017, 9, 35492–35497.

  32. Xiyu Zhu, Ruoyu Wang, Xiaohong Zhou*, Hanchang Shi. Free-energy-driven lock/open assembly-based optical DNA sensor for cancer-related microRNA detection with a shortened time-to-result, ACS Applied Materials & Interface, 2017, 9, 25789-25795.

  33. Lanhua Liu, Xiaohong Zhou*, Yun Lu*, Didi Shan, Bi Xu, Miao He, Hanchang Shi, Yi Qian. Facile screening of potential xenoestrogens by an estrogen receptor-based reusable optical biosensor. Biosensors and Bioelectronics, 2017, 97, 16-20.

  34. Lanhua Liu, Xiaohong Zhou*, James S. Wilkinson, Ping Hua*, Baodong Song, Hanchang Shi. Integrated optical waveguide-based fluorescent immunosensor for fast and sensitive detection of microcystin-LR in lakes: optimization and analysis. Scientific Reports, 2017, 7: 3655.

  35. Ruoyu Wang, Xiaohong Zhou*, Xiyu Zhu, Chao Yang, Lanhua Liu, Hanchang Shi. Isoelectric bovine serum albumin: Robust blocking agent for enhanced performance in optical-fiber based DNA sensing. ACS Sensors. 2017, 2(2): 257–262.

  36. Abdul Ghaffar Memon, Xiaohong Zhou*, Jinchuan Liu, Ruoyu Wang, Lanhua Liu, Bofan Yu, Miao He*, Hanchang Shi. Utilization of unmodified gold nanoparticles for label-free detection of mercury (II): Insight into rational design of mercury-specific oligonucleotides. Journal of Hazardous Materials, 2017, 321, 417-423.

  37. Lanhua Liu, Xiaohong Zhou*, Mifang Lu, Mingkai Zhang, Chao Yang, Ruiman Ma, Abdul Ghaffar Memon, Hanchang Shi, Yi Qian. An array fluorescent biosensor based on planar waveguide for multi-analyte determination in water samples. Sensors and Actuators B: Chemical, 2017, 240, 107-113.


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