首次發現了細菌間的相互合作與競争導緻生物被膜周期性減緩生長的新現象及其機制(Nature 2015, Science 2017);開發了定量研究細菌群體的新方法(Small Science 2022, Nature Chemical Biology 2023);揭示了細菌群體跨區域代謝交互的新模式(Nature Chemical Biology 2023);發現了細菌對抗生素以及噬菌體耐受性的新機制(Nature Chemical Biology 2024, Nature Communications 2024, Science Advances 2024)。
獎勵與榮譽
2018年入選國家海外高層次人才計劃青年項目
2018年入選求是科技基金會傑出青年學者
學術成果
Q. Hu, L. Huang, Y. Yang, Y. Xiang, J. Liu. Essential phage component induces resistance of bacterial community. Science Advances 10, eadp5057 (2024).
Y. Zhang, Y. Cai, X. Jin, Q. Wu, F. Bai, J. Liu. Persistent glucose consumption under antibiotic treatment protects bacterial community. Nature Chemical Biology (2024). https://doi.org/10.1038/s41589-024-01708-z
Y. Zheng, R. Chai, T. Wang, Z. Xu, Y. He, P. Shen, J. Liu. RNA polymerase stalling-derived genome instability underlies ribosomal antibiotic efficacy and resistance evolution. Nature Communications 15, 6579 (2024).
T. Wang, P. Shen, Y. He, Y. Zhang, J. Liu. Spatial transcriptome uncovers rich coordination of metabolism in E. coli K12 biofilm. Nature Chemical Biology 19, 940-950 (2023).
T. Wang, P. Shen, R. Chai, Y. He, J. Liu. Profiling of bacterial transcriptome from ultra-low input with MiniBac-seq. Environmental Microbiology 24, 5774–5787 (2022).
Y. Zhang, Y. Cai, L. Zeng, P. Liu, L. Z. Ma, J. Liu. A Microfluidic Approach for Quantitative Study of Spatial Heterogeneity in Bacterial Biofilms. Small Science 2, 2200047 (2022).
J. Liu, R. Martinez-Corral, A. Prindle, D.-Y. D. Lee, J. Larkin, M. Gabalda-Sagarra, J. Garcia-Ojalvo, G. M. Süel, Coupling between distant biofilms and emergence of nutrient time-sharing. Science 356, 638–642 (2017).
J. Liu, A. Prindle, J. Humphries, M. Gabalda-Sagarra, M. Asally, D. D. Lee, S. Ly, J. Garcia-Ojalvo, G. M. Süel, Metabolic co-dependence gives rise to collective oscillations within biofilms. Nature 523, 550–554 (2015).
Complete list of publications: https://orcid.org/0000-0002-6710-2605